A partner for every challenge

Description & team coming soon

About & role in FOCUS-4R

Based in La Réunion and hosted by the Sainte-Clotilde Clinic, RunResearch focuses on clinical challenges — tumour radioresistance, the tumour microenvironment, and the prediction of tumour radiation response — toward future personalised medical management.

Its expertise covers clinical radiotherapy, CT imaging, cell culture and histology. Within FOCUS-4R it aims to expand into tumour modelling and 3D culture, build a tumour bank, and strengthen imaging and entrepreneurial skills.

About & role in FOCUS-4R

The project is developed within INSERM, the French National Institute of Health and Medical Research and one of Europe’s leading biomedical research organisations. It offers a highly interdisciplinary environment for translational and clinical research — oncology, molecular signalling, precision medicine and therapeutic innovation — supported by advanced technological platforms and expertise in tumour biology and targeted therapies.

Within FOCUS-4R, INSERM helps build research and innovation capacity through advanced biomedical approaches, cross-disciplinary collaboration and ethical practices aligned with the 4R principles, while promoting talent mobility, international exchange and translational research linking fundamental discoveries to clinical applications.

The work is closely associated with the University of Bordeaux, whose strengths in life sciences, cancer research and biomedical innovation — and its regional, national and European networks — reinforce the scientific and translational dimension of the initiative.

Description & team coming soon

About & role in FOCUS-4R

CQM’s research spans the marine, food and health domains. Grounded in strong chemical-synthesis know-how, it develops advanced materials — dendrimers, nanoparticles, carbon nanomaterials, gels and nanogels — explored as platforms for drug/gene delivery and theranostics.

By joining FOCUS-4R, CQM strengthens the 4R principles: new approach methodologies to reduce animal models (Replacement), optimised design (Reduction & Refinement), and strict ethical compliance (Responsibility).

About & role in FOCUS-4R

An interdisciplinary research institute advancing health sciences through integrated basic, translational and clinical research, bringing together UPorto schools, hospitals and founding institutes (IBMC, INEB, IPATIMUP). Focus areas: cancer, infection & immunity, neurobiology.

Within FOCUS-4R, i3S provides a high-quality environment for capacity building, training and mobility for partners from outermost regions, in line with the 4R principles.

About & role in FOCUS-4R

A public university in Tenerife committed to higher education, research and knowledge transfer. In FOCUS-4R it participates through the Instituto Universitario de Tecnologías Biomédicas (ITB), focused on basic and translational biomedical research.

Its staff support capacity building, knowledge transfer and the promotion of innovative, ethical research practices in outermost regions.

About & role in FOCUS-4R

A non-profit research center and member of the Basque Research and Technology Alliance (BRTA), working at the interface of chemistry, physics and biology, with emphasis on biomaterials, nanomedicine and molecular imaging.

In FOCUS-4R it contributes advanced imaging (nuclear, MRI, NMR, optical), radiochemistry, electron microscopy and surface analysis — focused on training and knowledge transfer.

About & role in FOCUS-4R

Ocean TuniCell provides clinically relevant hydrogel biomaterial that bridges the research community and clinicians, facilitating the translational process in regenerative medicine.

Its invention is medical-grade nanofibrillar cellulose — TUNICELL — for 3D reconstruction of tissues and organs. In FOCUS-4R it trains researchers in 3D cultures with TUNICELL, an alternative to animal use in line with the 4R principles.

About & role in FOCUS-4R

The largest single investment in advanced medical research and diagnostics in Norway, created to develop and produce radiopharmaceuticals for PET imaging. Owned by Oslo University Hospital, Akershus University Hospital and the University of Oslo.

Its research department combines radioactivity production, radiochemistry, automation and preclinical tracer characterisation, collaborating on cancer, neurological and cardiovascular diseases.

About & role in FOCUS-4R

Originally established as Ocello in 2011, the company became part of Crown Bioscience Netherlands in 2021, combining pre-clinical in-vitro assays and high-content imaging to accelerate drug development.

Operating in contract-research in-vitro oncology drug discovery, it spans efficacy testing, biomarker analysis, translational genomics, DMPK and toxicology. Through FOCUS-4R it trains scientists from outermost regions in organoid-based models.